Where to buy good 4-AcO-DMT

The psychedelic compound 4-Acetoxy-N, N-dimethyltryptamine, sometimes referred to as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, and psilocin is a new member of the tryptamine family. It is a structural homolog of the psychoactive substance found in psilocybin mushrooms, psilocybin (magic mushrooms).

Similar to psilocybin, it is believed to work mostly through attaching to serotonin receptors in the brain, though the specific process is yet unclear. Given that both psilocybin and O-Acetylpsilocin are thought to be prodrugs of psilocin, David Nichols has proposed that O-Acetylpsilocin may be a useful substitute for psilocybin in pharmacological research.

C14H18N2O2 as a formula

• 3049 g/mol for molar mass
• 172 °C, melting point
• 21106357 is the ChemSpider ID.

Various names

• 3-(2′-dimethylaminoethyl)-4-acetoxy-indole
• 4-acetoxy-N,N-dimethyltryptamine

21106357 in ChemSpider

Subjective effects reportedly include geometric visual hallucinations, temporal dilation, improved introspection, euphoria, and ego loss and are almost comparable to those of psilocybin mushrooms. This similarity may be explained by the fact that 4-AcO-DMT is thought to function similarly to psilocybin as a prodrug to psilocin.

Users of novel psychoactive substances looking for mystical or entheogenic experiences are drawn to 4-AcO-DMT because of its traditional psychedelic effects and well-tolerated profile.

On the pharmacology, metabolism, and toxicity of 4-AcO-DMT, there is very little information. There is currently no evidence to back up the notion that it has a positive safety profile comparable to that of psilocybin mushrooms, which are understood to be physiologically non-toxic. If using this substance, harm reduction strategies are strongly encouraged.

Where to buy good 4-AcO-DMT?

Subjective effects reportedly include geometric visual hallucinations, temporal dilation, improved introspection, euphoria, and ego loss and are almost comparable to those of psilocybin mushrooms. This similarity may be explained by the fact that 4-AcO-DMT is thought to function similarly to psilocybin as a prodrug to psilocin.

Users of novel psychoactive substances looking for mystical or entheogenic experiences are drawn to 4-AcO-DMT because of its traditional psychedelic effects and well-tolerated profile.

History of 4-AcO-DMT

On January 16, 1963, Sandoz Ltd., through Albert Hofmann & Franz Troxler, obtained patents for O-Acetylpsilocin (psilacetin) and a number of additional psilocin esters. Psilacetin still continues to be a psychedelic substance with scant history of use. It is hypothesized to be a prodrug of psilocybin, which naturally exists in a variety of hallucinogenic mushroom species.

This is due to the fact that in acidic environments like the stomach, the aromatic acetyl moiety on the 4th position of the indole ring system is susceptible to deacetylation. While psilocybin is O-phosphorylated, psilocin is O-acetylated psilocin.

 Chemistry of 4-AcO-DMT

Psilocin can be acetylated under alkaline or strongly acidic conditions to produce O-Acetylpsilocin. As a result, it is a semi-synthetic molecule. However, there is concern that psilacetin itself might possibly be psychoactive. It is thought to be a prodrug of psilocin. O-acetoxy Acetylpsilocin’s group makes it more resistant to oxidation than psilocin is under simple circumstances.

In contrast to psilocin and psilocybin, O-acetylpsilocin has not received as much research attention and is occasionally derided as a research chemical, though it is easier to synthesis than psilocybin. The idea that O-acetylpsilocin might function as a viable replacement for psilocybin in studies of the use of psychedelic substances in medicine may be further supported by the fact that their similar suggested mechanisms of action.

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